The conventional wisdom is that glucocorticoids neither alter thecourse of the disease nor affect the ultimate degree of damage to jointsor other structureskey concept objective to understand medical therapy for ra board reviewadvancement from nsaids to second-line agents is recommended if symptoms havenot improved sufficiently after a short trial of nsaids purchase urispas 200 mg with mastercard, the patient has aggressiveseropositive disease, or there is radiographic evidence of erosions or joint destructionthe trend today is for more aggressive treatment, and the majority of patients require addi-tional pharmacotherapy.
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